The Swiss veteran competed at the Australian Open, French Open and Wimbledon this year on wildcards but will miss the US Open, where he won the title in 2016, depriving him of a farewell appearance at the year's final major.
The 41-year-old three-time Grand Slam champion was not among the final wildcards announced over the weekend and will also not compete in this week's qualifying tournament.
"This city challenged me. It pushed me. It brought something out of me that few places ever could," Wawrinka wrote on Instagram.
"I experienced some of the strongest emotions of my career here. Winning the US Open in the city that never sleeps will forever be one of the greatest moments of my life."
French veteran Gael Monfils, who has also said he will retire at the end of the season, received a reciprocal wildcard, which are granted by the national federatons. The former world number six is ranked 307th, compared with Wawrinka at 127.
On the women's side, twice US Open champion Venus Williams was awarded a wildcard for this year's tournament.
The US Open men's and women's singles main draw begins on Sunday.
US Open 2026
The US Open is the fourth and final Grand Slam of the tennis season, running from August 30th to September 13th. It is a hard-court tournament held at Flushing Meadows in New York City. Follow the links below for more information!
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