The Reds should have a boost with only Joe Gomez certain to miss their clash against the Foxes - and Trent Alexander-Arnold set to return to the bench - while the visitors remain without Harry Winks, Harry Souttar and Abdul Fatawu for their must-win showdown with the champions-elect.
Arsenal's injury problems remain for their trip to Ipswich, with Gabriel, Kai Havertz and Riccardo Calafiori set to miss out alongside several other players.
The Tractor Boys have plenty of injuries to contend with themselves and will be relegated if they lose and the results elsewhere go against them.
Take a look at who's missing, suspended and doubtful ahead of the next round of Premier League fixtures:
Brentford vs Brighton
WON'T PLAY
Carvalho F. | Shoulder Injury
Dasilva J. | Knee Injury
Hickey A. | Hamstring Injury
Thiago I. | Knee Injury
Igor | Thigh Injury
Kadioglu F. | Toe Injury
Lamptey T. | Ankle Injury
Milner J. | Thigh Injury
Rutter G. | Ankle Injury
Steele J. | Shoulder Injury
Veltman J. | Ankle Injury
Webster A. | Thigh Injury
Crystal Palace vs Bournemouth
WON'T PLAY
Doucoure C. | Knee Injury
Riad C. | Knee Injury
Christie R. | Groin Injury
Sinisterra L. | Hamstring Injury
Unal E. | Knee Injury
DOUBTFUL
Kluivert J. | Injury
Everton vs Manchester City
WON'T PLAY
Calvert-Lewin D. | Muscle Injury
Lindstrom J. | Groin Injury
Mangala O. | Knee Injury
Ake N. | Ankle Injury
Haaland E. | Ankle Injury
Rodri | Knee Injury
Stones J. | Thigh Injury
DOUBTFUL
Akanji M. | Muscle Injury
Ederson | Groin Injury
West Ham vs Southampton
WON'T PLAY
Antonio M. | Inactive
Summerville C. | Hamstring Injury
Gronbaek A. | Muscle Injury
DOUBTFUL
Cresswell A. | Muscle Injury
Onuachu P. | Ankle Injury
Taylor C. | Knock
Aston Villa vs Newcastle
WON'T PLAY
N/A.
Botman S. | Knee Injury
Hall L. | Foot Injury
Lascelles J. | Knee Injury
Fulham vs Chelsea
WON'T PLAY
Nelson R. | Hamstring Injury
Fofana D. D. | Knee Injury
Fofana W. | Hamstring Injury
Guiu M. | Muscle Injury
Kellyman O. | Hamstring Injury
Lavia R. | Thigh Injury
Mudryk M. | Suspended
Ipswich vs Arsenal
WON'T PLAY
Burns W. | Knee Injury
Muric A. | Shoulder Injury
Ogbene C. | Calf Injury
Phillips K. | Injury
Philogene J. | Knee Injury
Szmodics S. | Ankle Injury
Calafiori R. | Knee Injury
Gabriel | Hamstring Injury
Gabriel Jesus | Knee Injury
Havertz K. | Hamstring Injury
Jorginho | Chest Injury
Tomiyasu T. | Knee Injury
Manchester United vs Wolves
WON'T PLAY
Collyer T. | Knock
de Ligt M. | Injury
Diallo A. | Ankle Injury
Evans J. | Lower Back Injury
Heaven A. | Ankle Injury
Martinez L. | Knee Injury
Zirkzee J. | Hamstring Injury
Chiwome L. | Knee Injury
Gonzalez E. | Knee Injury
Kalajdzic S. | Knee Injury
Mosquera Y. | Knee Injury
DOUBTFUL
Doherty M. | Knock
Leicester vs Liverpool
WON'T PLAY
Fatawu I. | Knee Injury
Souttar H. | Ankle Injury
Winks H. | Coach's decision
Gomez J. | Hamstring Injury
DOUBTFUL
Alexander-Arnold T. | Ankle Injury
Nunez D. | Illness
Tottenham vs Nottingham Forest
WON'T PLAY
Dragusin R. | Knee Injury
Son Heung-Min | Foot Injury
Aina O. | Calf Injury
DOUBTFUL
Maddison J. | Injury