The expanded 14-team top flight kicks off on September 4th.
Two-time Ballon d'Or winner Alexia Putellas could make her WSL debut when London City Lionesses host Manchester United in the opening match, while London City goalkeeper Mary Earps may face her former club.
Promoted Charlton Athletic start at home to Liverpool, while Crystal Palace return to the WSL following a one-season absence with a game against Everton.
Tottenham Hotspur host West Ham United in a London derby, Chelsea welcome Aston Villa to Stamford Bridge and Brighton & Hove Albion face Arsenal.
WSL Football said it ran more than 1.5 billion fixture scheduling iterations to produce the calendar, taking into account stadium availability, broadcast requirements and clashes with domestic and European competitions in both the men's and women's game.