Argentina had been due to play Spain in the 'Finalissima' in Qatar, but the game was cancelled due to the conflict in the Middle East.
"The national team will play a friendly against Mauritania as the squad begins its farewell to fans before departing to defend its World Cup title," the AFA said in a statement.
The match will be played at Boca Juniors' La Bombonera stadium on March 27th. Mauritania had been scheduled to face Palestine in Morocco, but that game was also cancelled due to the conflict.
Argentina had planned a friendly against Guatemala on March 31st, but that match was cancelled after failing to receive FIFA approval because Guatemala were already scheduled to face Algeria in Italy.
Argentina begin their World Cup title defence on June 16th against Algeria.